REDUCE - REDuction of UnCertain Edges

Main content

REDUCE is an algorithm for optimal design of gene knock-out (KO) for the purpose of gene regulatory network (GRN) inference. Please refer to our manuscript entitled "Optimal design of gene knock-out experiments for gene regulatory network inference" for more details regarding the algorithm. The archive zip file provides MATLAB scripts for REDUCE.

Prerequisites: MATLAB 2014b (also tested on Octave 3.2.4), Python 2.7

Last Update

Date of last modification: 08.10.2015  

License

Redistribution and use in source and binary forms, with or without modification, are permitted provided agreeing to the Simplified BSD Style License.

License (RTF, 2 KB)

Read about Simplified BSD Style License at http://www.opensource.org/licenses/bsd-license.php

Download & Installation

Download & unzip the REDUCE.zip (ZIP, 22 KB)

Please use the following reference when using REDUCE

  • Ud-Dean, SMM., and Gunawan, R. Optimal design of gene knock-out experiments for gene regulatory network inference. Bioinformatics 32 (6): 875-883 (2016). abstract

Acknowledgement

This work is supported by funding from Swiss National Science Foundation.

 
 
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22.06.2017
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