REDUCE - REDuction of UnCertain Edges
REDUCE is an algorithm for optimal design of gene knock-out (KO) for the purpose of gene regulatory network (GRN) inference. Please refer to our manuscript entitled "Optimal design of gene knock-out experiments for gene regulatory network inference" for more details regarding the algorithm. The archive zip file provides MATLAB scripts for REDUCE.
Prerequisites: MATLAB 2014b (also tested on Octave 3.2.4), Python 2.7
Last Update
Date of last modification: 08.10.2015
License
Redistribution and use in source and binary forms, with or without modification, are permitted provided agreeing to the Simplified BSD Style License.
DownloadLicense (RTF, 2 KB)vertical_align_bottom
Read about Simplified BSD Style License at external pagehttp://www.opensource.org/licenses/bsd-license.phpcall_made
Download & Installation
Download & unzip the DownloadREDUCE.zip (ZIP, 22 KB)vertical_align_bottom
Please use the following reference when using REDUCE
- Ud-Dean, SMM., and Gunawan, R. Optimal design of gene knock-out experiments for gene regulatory network inference. Bioinformatics 32 (6): 875-883 (2016). external pageabstractcall_made
Acknowledgement
This work is supported by funding from Swiss National Science Foundation.